Necroptotic Cell Death Signaling and Execution Pathway: Lessons from Knockout Mice

• Main Authors: José Belizário (Author), Luiz Vieira-Cordeiro (Author), Sylvia Enns (Author)
• Format: Book
• Published: Hindawi Limited, 2015-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Under stress conditions, cells in living tissue die by apoptosis or necrosis depending on the activation of the key molecules within a dying cell that either transduce cell survival or death signals that actively destroy the sentenced cell. Multiple extracellular (pH, heat, oxidants, and detergents)...