Generic orphan drug substitution: a critical analysis of global practices and Saudi Arabia's perspective

• Main Authors: Yousif S. Alakeel (Author), Emmanouil Rampakakis (Author), Ali AlRumaih (Author), Rana AlRuwaisan (Author), Maha Abushal (Author), Abdullah M. AlDalaan (Author), Majdy M. Idrees (Author), Zaid D. Alanazi (Author), Hanouf AlKoait (Author), Abdulrahman Muaadi (Author), Majed Ali M. AlAfra (Author), Shaya A. AlShaya (Author), Suliman AlHomida (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In an era of cost pressure, substituting generic drugs represents one of the main cost-containment strategies of healthcare systems. Despite the obvious financial benefits, in a minority of cases, substitution may require caution or even be contraindicated. In most jurisdictions, to obtain approval,...