Mechanisms of BK Channel Activation by Docosahexaenoic Acid in Rat Coronary Arterial Smooth Muscle Cells

• Main Authors: Ling-Ling Qian (Author), Man-Qing Sun (Author), Ru-Xing Wang (Author), Tong Lu (Author), Ying Wu (Author), Shi-Peng Dang (Author), Xu Tang (Author), Yuan Ji (Author), Xiao-Yu Liu (Author), Xiao-Xi Zhao (Author), Wen Wang (Author), Qiang Chai (Author), Min Pan (Author), Fu Yi (Author), Dai-Min Zhang (Author), Hon-Chi Lee (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Aim: Docosahexaenoic acid (DHA) is known to activate the vascular large-conductance calcium-activated potassium (BK) channels and has protective effects on the cardiovascular system. However, the underlying mechanisms through which DHA activates BK channels remain unclear. In this study, we determin...