Cover Image

Mechanisms of BK Channel Activation by Docosahexaenoic Acid in Rat Coronary Arterial Smooth Muscle Cells

Aim: Docosahexaenoic acid (DHA) is known to activate the vascular large-conductance calcium-activated potassium (BK) channels and has protective effects on the cardiovascular system. However, the underlying mechanisms through which DHA activates BK channels remain unclear. In this study, we determin...

Full description

Saved in:

Bibliographic Details
Main Authors:	Ling-Ling Qian (Author), Man-Qing Sun (Author), Ru-Xing Wang (Author), Tong Lu (Author), Ying Wu (Author), Shi-Peng Dang (Author), Xu Tang (Author), Yuan Ji (Author), Xiao-Yu Liu (Author), Xiao-Xi Zhao (Author), Wen Wang (Author), Qiang Chai (Author), Min Pan (Author), Fu Yi (Author), Dai-Min Zhang (Author), Hon-Chi Lee (Author)
Format:	Book
Published:	Frontiers Media S.A., 2018-03-01T00:00:00Z.
Subjects:	article
Online Access:	Connect to this object online.
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Hydrogen Sulfide-Induced Vasodilation: The Involvement of Vascular Potassium Channels
by: Xiao-Yu Liu, et al.
Published: (2022)

Hydrogen Sulfide Relaxes Human Uterine Artery via Activating Smooth Muscle BK<sub>Ca</sub> Channels
by: Yan Li, et al.
Published: (2020)

BK Channel in the Physiology and in the Cancer of Pancreatic Duct: Impact and Reliability of BK Openers
by: Paolo Zuccolini, et al.
Published: (2022)

BK Channels: Integrators of Cellular Signals in Health and Disease
by: Alex Dopico
Published: (2017)

BK<sub>Ca</sub> Channels as Targets for Cardioprotection
by: Kalina Szteyn, et al.
Published: (2020)

Large conductance voltage-and calcium-activated K+ (BK) channel in health and disease
by: Felipe Echeverría, et al.
Published: (2024)

The Membrane Cholesterol Modulates the Interaction Between 17-βEstradiol and the BK Channel
by: Sara T. Granados, et al.
Published: (2021)

Docosahexaenoic acid and eicosapentaenoic acid strongly inhibit prostanoid TP receptor‐dependent contractions of guinea pig gastric fundus smooth muscle
by: Keyue Xu, et al.
Published: (2022)

Arachidonic Acid and Docosahexaenoic Acid Metabolites in the Airways of Adults With Cystic Fibrosis: Effect of Docosahexaenoic Acid Supplementation
by: Elisabetta Teopompi, et al.
Published: (2019)

Luteolin-Induced Activation of Mitochondrial BK<sub>Ca</sub> Channels: Undisclosed Mechanism of Cytoprotection
by: Rafał P. Kampa, et al.
Published: (2022)

Monitoring BK virus infection in pediatric kidney transplant recipients
by: Min Hyun Cho
Published: (2019)

Paracetamol inhibits Ca2+ permeant ion channels and Ca2+ sensitization resulting in relaxation of precontracted airway smooth muscle
by: Yuan-Yuan Chen, et al.
Published: (2020)

The Role of Astrocytes in the Central Nervous System Focused on BK Channel and Heme Oxygenase Metabolites: A Review
by: Yonghee Kim, et al.
Published: (2019)

Maternal Docosahexaenoic Acid Increases Adiponectin and Normalizes IUGR-Induced Changes in Rat Adipose Deposition
by: Heidi N. Bagley, et al.
Published: (2013)

Co-delivery of paclitaxel (PTX) and docosahexaenoic acid (DHA) by targeting lipid nanoemulsions for cancer therapy
by: Bo Li, et al.
Published: (2022)

Influence of smooth muscle contractility by inhibition of crac channels activity
by: Kocmálová M., et al.
Published: (2017)

The T-type Ca2+ Channel Inhibitor Mibefradil Inhibits Voltage-Dependent K+ Channels in Rabbit Coronary Arterial Smooth Muscle Cells
by: Da Hye Hong, et al.
Published: (2012)

Polysaccharide dextran-based conjugate for selective co-delivery of two synergistic drugs docetaxel and docosahexaenoic acid to tumor cells
by: Peng Dong, et al.
Published: (2023)

The role of the docosahexaenoic acid in nutrition of pregnant and feeding women
by: Н. М. Шилина
Published: (2018)

Salidroside contributes to reducing blood pressure and alleviating cerebrovascular contractile activity in diabetic Goto-Kakizaki Rats by inhibition of L-type calcium channel in smooth muscle cells
by: Yu-Guang Ma, et al.
Published: (2017)

The Ca2+ Channel Iinhibitor NNC 55-0396 Inhibits Voltage-Dependent K+ Channels in Rabbit Coronary Arterial Smooth Muscle Cells
by: Youn Kyoung Son, et al.
Published: (2014)

Docosahexaenoic Acid Enhances Cyclooxygenase-2 Induction by Facilitating p44/42, but Not p38, Mitogen-Activated Protein Kinase Activation in Rat Vascular Smooth Muscle Cells
by: Takuji Machida, et al.
Published: (2005)

The Guanylyl Cyclase Activator YC-1 Directly Inhibits the Voltage-Dependent K+ Channels in Rabbit Coronary Arterial Smooth Muscle Cells
by: Won Sun Park, et al.
Published: (2010)

Evaluation of four KCNMA1 channelopathy variants on BK channel current under CaV1.2 activation
by: Ria L. Dinsdale, et al.
Published: (2024)

A Novel Opener of Large-Conductance Ca2+-Activated K+ (BK) Channel Reduces Ischemic Injury in Rat Cardiac Myocytes by Activating Mitochondrial KCa Channel
by: Kazuho Sakamoto, et al.
Published: (2008)

Docosahexaenoic acid mechanisms of action on the bovine oocyte-cumulus complex
by: Sebastien Elis, et al.
Published: (2017)

Activation of BK Channels Prevents Hepatic Stellate Cell Activation and Liver Fibrosis Through the Suppression of TGFβ1/SMAD3 and JAK/STAT3 Profibrotic Signaling Pathways
by: Linli Yang, et al.
Published: (2020)

Role of Macrophage Migration Inhibitory Factor in the Proliferation of Smooth Muscle Cell in Pulmonary Hypertension
by: Bo Zhang, et al.
Published: (2012)

Functional Regulation of KATP Channels and Mutant Insight Into Clinical Therapeutic Strategies in Cardiovascular Diseases
by: Zhicheng Wang, et al.
Published: (2022)

Bladder Contractility Is Mediated by Different K+ Channels in the Urothelium and Detrusor Smooth Muscle
by: Aneira Gracia Hidayat Santoso, et al.
Published: (2011)

Calcium and potassium channels are involved in curcumin relaxant effect on tracheal smooth muscles
by: Bahman Emami, et al.
Published: (2020)

Canonical Transient Receptor Potential Channels and Vascular Smooth Muscle Cell Plasticity
by: Motohiro Nishida, et al.
Published: (2020)

KINERJA GURU BK DALAM MELAKSANAKAN PROGRAM BK LAYANAN BIMBINGAN KARIR DI SMA
by: Nadya Rahmadani
Published: (2021)

BK polyomavirus-associated nephropathy
by: Yo Han Ahn, et al.
Published: (2022)

Inhibiting vascular smooth muscle cell proliferation mediated by osteopontin via regulating gut microbial lipopolysaccharide: A novel mechanism for paeonol in atherosclerosis treatment
by: Xiaoyan Shi, et al.
Published: (2022)

Docosahexaenoic acid (DHA) effects on proliferation and steroidogenesis of bovine granulosa cells
by: Virginie Maillard, et al.
Published: (2018)

Combination therapy with butyrate and docosahexaenoic acid for keloid fibrogenesis: an in vitro study
by: Kazuhiro Torii, et al.
Published: (2017)

Effect of docosahexaenoic acid plus insulin on atherosclerotic human endothelial cells
by: Aysan Eslami Abriz, et al.
Published: (2021)

Docosahexaenoic acid-mediated, targeted and sustained brain delivery of curcumin microemulsion
by: Rajshree L. Shinde, et al.
Published: (2017)

Joint effect of docosahexaenoic acid intake and tobacco smoke exposure on learning disability in children and adolescents: a cross-sectional study from the NHANES database
by: Ling Liu, et al.
Published: (2024)