Investigation of the Factors Responsible for the Poor Oral Bioavailability of Acacetin in Rats: Physicochemical and Biopharmaceutical Aspects

• Main Authors: Dong-Gyun Han (Author), Eunju Cha (Author), Jeongmin Joo (Author), Ji Sun Hwang (Author), Sanghyun Kim (Author), Taeuk Park (Author), Yoo-Seong Jeong (Author), Han-Joo Maeng (Author), Sang-Bum Kim (Author), In-Soo Yoon (Author)
• Format: Book
• Published: MDPI AG, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Acacetin, an important ingredient of acacia honey and a component of several medicinal plants, exhibits therapeutic effects such as antioxidative, anticancer, anti-inflammatory, and anti-plasmodial activities. However, to date, studies reporting a systematic investigation of the in vivo fate of oral...