Rapid-Onset Anti-Stress Effects of a Kappa-Opioid Receptor Antagonist, LY2795050, Against Immobility in an Open Space Swim Paradigm in Male and Female Mice

• 主要な著者: Caroline Baynard (著者), Thomas E. Prisinzano (著者), Eduardo R. Butelman (著者)
• フォーマット: 図書
• 出版事項: Frontiers Media S.A., 2021-11-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

The kappa-opioid receptor (KOR) / dynorphin system is implicated with behavioral and neurobiological effects of stress exposure (including heavy exposure to drugs of abuse) in translational animal models. Thus some KOR-antagonists can decrease the aversive, depressant-like and anxiety-like effects c...