Physiological roles of the GIP receptor in murine brown adipose tissue

• Main Authors: Jacqueline L. Beaudry (Author), Kiran D. Kaur (Author), Elodie M. Varin (Author), Laurie L. Baggio (Author), Xiemin Cao (Author), Erin E. Mulvihill (Author), Holly E. Bates (Author), Jonathan E. Campbell (Author), Daniel J. Drucker (Author)
• Format: Book
• Published: Elsevier, 2019-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Glucose-dependent insulinotropic polypeptide (GIP) is secreted from the gut in response to nutrient ingestion and promotes meal-dependent insulin secretion and lipid metabolism. Loss or attenuation of GIP receptor (GIPR) action leads to resistance to diet-induced obesity through incomplet...