Multiple Family Members With Delayed Cord Separtion and Combined Immunodeficiency With Novel Mutation in IKBKB

• Main Authors: Zobaida Alsum (Author), Mofareh S. AlZahrani (Author), Hamoud Al-Mousa (Author), Nouf Alkhamis (Author), Abdulkareem A. Alsalemi (Author), Hanan E. Shamseldin (Author), Fowzan S. Alkuraya (Author), Abdullah A. Alangari (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Inhibitor of kappa kinase 2 (IKK2) deficiency is a recently described combined immunodeficiency. It undermines the nuclear factor-kappa B (NF-κB) activation pathway.Methods: The clinical and immunological data of four patients diagnosed with combined immunodeficiency (CID) from two relat...