Analysis of polymorphisms in 16 genes in type 1 diabetes that have been associated with other immune-mediated diseases

• Main Authors: Walker Neil M (Author), Nutland Sarah (Author), Lam Alex C (Author), Dahlman Ingrid (Author), Vella Adrian (Author), Hulme John S (Author), Cooper Jason D (Author), Lowe Christopher E (Author), Holland Kieran (Author), Bailey Rebecca (Author), Maier Lisa M (Author), Payne Felicity (Author), Howson Joanna MM (Author), Smyth Deborah J (Author), Twells Rebecca CJ (Author), Todd John A (Author)
• Format: Book
• Published: BMC, 2006-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>The identification of the HLA class II, insulin (INS), CTLA-4 and PTPN22 genes as determinants of type 1 diabetes (T1D) susceptibility indicates that fine tuning of the immune system is centrally involved in disease development. Some...