Analysis of polymorphisms in 16 genes in type 1 diabetes that have been associated with other immune-mediated diseases

• 主要な著者: Walker Neil M (著者), Nutland Sarah (著者), Lam Alex C (著者), Dahlman Ingrid (著者), Vella Adrian (著者), Hulme John S (著者), Cooper Jason D (著者), Lowe Christopher E (著者), Holland Kieran (著者), Bailey Rebecca (著者), Maier Lisa M (著者), Payne Felicity (著者), Howson Joanna MM (著者), Smyth Deborah J (著者), Twells Rebecca CJ (著者), Todd John A (著者)
• フォーマット: 図書
• 出版事項: BMC, 2006-03-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>The identification of the HLA class II, insulin (INS), CTLA-4 and PTPN22 genes as determinants of type 1 diabetes (T1D) susceptibility indicates that fine tuning of the immune system is centrally involved in disease development. Some...