Colon targeting in rats, dogs and IBD patients with species-independent film coatings
Polysaccharides were identified, which allow for colon targeting in human Inflammatory Bowel Disease (IBD) patients, as well as in rats and dogs (which are frequently used as animals in preclinical studies). The polysaccharides are degraded by colonic enzymes (secreted by bacteria), triggering the o...
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Main Authors: | , , , , , , |
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Format: | Book |
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Elsevier,
2024-06-01T00:00:00Z.
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A1234.567 |
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