Ryanodine receptor type 1 content decrease‐induced endoplasmic reticulum stress is a hallmark of myopathies

• Main Authors: Jeremy Vidal (Author), Eric A. Fernandez (Author), Martin Wohlwend (Author), Pirkka‐Pekka Laurila (Author), Andrea Lopez‐Mejia (Author), Julien Ochala (Author), Alexander J. Lobrinus (Author), Bengt Kayser (Author), Isabel C. Lopez‐Mejia (Author), Nicolas Place (Author), Nadège Zanou (Author)
• Format: Book
• Published: Wiley, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Decreased ryanodine receptor type 1 (RyR1) protein levels are a well‐described feature of recessive RYR1‐related myopathies. The aim of the present study was twofold: (1) to determine whether RyR1 content is also decreased in other myopathies and (2) to investigate the mechanisms...