Bone marrow mesenchymal stem cell-derived exosomes shuttling miR-150-5p alleviates mechanical allodynia in rats by targeting NOTCH2 in microglia

• Hoofdauteurs: Shuangqing Li (Auteur), Ciying Huang (Auteur), Chao Tu (Auteur), Ruiqi Chen (Auteur), Xiaolei Ren (Auteur), Lin Qi (Auteur), Zhihong Li (Auteur)
• Formaat: Boek
• Gepubliceerd in: BMC, 2022-11-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Abstract Background This study probes into the function and mechanism of bone marrow mesenchymal stem cell (BMSC)-derived exosomes loaded with miR-150-5p in mechanical allodynia. Methods BMSCs were infected with miR-150-5p inhibition lentiviruses to obtain exosomes with low miR-150-5p expression. A...