Synthesis, Molecular Docking Study, and Biological Evaluation of New 4-(2,5-Dimethyl-1<i>H</i>-pyrrol-1-yl)-<i>N</i>'-(2-(substituted)acetyl)benzohydrazides as Dual Enoyl ACP Reductase and DHFR Enzyme Inhibitors

• Main Authors: Mater H. Mahnashi (Author), Pooja Koganole (Author), Prem Kumar S. R. (Author), Sami S. Ashgar (Author), Ibrahim Ahmed Shaikh (Author), Shrinivas D. Joshi (Author), Ali S. Alqahtani (Author)
• Format: Book
• Published: MDPI AG, 2023-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In this study, a new series of 4-(2,5-dimethyl-1<i>H</i>-pyrrol-1-yl)-<i>N'</i>-(2-(substituted)acetyl) benzohydrazides (<b>5a-n</b>) were prepared and new heterocycles underwent thorough characterization and evaluation for antibacterial activity; some of the...