Synthesis and biological activity of bisindole derivatives as novel MARK4 inhibitors

Synthesis and biological activity of bisindole derivatives as novel MARK4 inhibitors

Bisindole alkaloids are well-known bioactive natural products presenting numerous pharmacological properties. Following the indolocarbazole biosynthetic pathway a series of bisindole derivatives were synthesized and their activity against MARK4 kinase was investigated. The binding of bisindoles on M...

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Main Authors: Maria Voura (Author), Saleha Anwar (Author), Savvas Thysiadis (Author), Parvez Κhan (Author), Panagiotis Dalezis (Author), Dimitrios T. Trafalis (Author), Md Imtaiyaz Hassan (Author), Vasiliki Sarli (Author)
Format: Book
Published: Elsevier, 2022-12-01T00:00:00Z.
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