Synthesis and Evaluation of Glucosyl-, Acyl- and Silyl- Resveratrol Derivatives as Retinoprotective Agents: Piceid Octanoate Notably Delays Photoreceptor Degeneration in a Retinitis Pigmentosa Mouse Model

• Prif Awduron: Lourdes Valdés-Sánchez (Awdur), Seyed Mohamadmehdi Moshtaghion (Awdur), Estefanía Caballano-Infantes (Awdur), Pablo Peñalver (Awdur), Rosario Rodríguez-Ruiz (Awdur), José Luis González-Alfonso (Awdur), Francisco José Plou (Awdur), Tom Desmet (Awdur), Juan C. Morales (Awdur), Francisco J. Díaz-Corrales (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: MDPI AG, 2024-11-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

Background: Retinitis pigmentosa (RP), the leading cause of inherited blindness in adults, is marked by the progressive degeneration of rod photoreceptors in the retina. While gene therapy has shown promise in treating RP in patients with specific mutations, no effective therapies currently exist fo...