Cystathionine Gamma-Lyase Regulates TNF-α-Mediated Injury Response in Human Colonic Epithelial Cells and Colonoids

• Main Authors: Francisco Arroyo Almenas (Author), Gábor Törő (Author), Peter Szaniszlo (Author), Manjit Maskey (Author), Ketan K. Thanki (Author), Walter A. Koltun (Author), Gregory S. Yochum (Author), Irina V. Pinchuk (Author), Celia Chao (Author), Mark R. Hellmich (Author), Katalin Módis (Author)
• Format: Book
• Published: MDPI AG, 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cystathionine gamma-lyase (CSE) and TNF-α are now recognized as key regulators of intestinal homeostasis, inflammation, and wound healing. In colonic epithelial cells, both molecules have been shown to influence a variety of biological processes, but the specific interactions between intracellular s...