Effects of galantamine on social interaction impairments in cholecystokinin receptor-2 overexpression mice

• Main Authors: Shota Tanase (Author), Takayoshi Mamiya (Author), Shogo Nagata (Author), Yusuke Ikawa (Author), Ya-Ping Tang (Author), Masayuki Hiramatsu (Author), Toshitaka Nabeshima (Author)
• Format: Book
• Published: Elsevier, 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

We examined whether galantamine (GAL), a cholinesterase inhibitor and allosteric potentiating ligand for α7 nicotinic acetylcholine receptor (nAChR), had an impact on emotional abnormalities in forebrain-specific cholecystokinin receptor-2 overexpressed transgenic mice. Treatment with GAL (1 mg/kg,...