Saliva for Precision Dosing of Antifungal Drugs: Saliva Population PK Model for Voriconazole Based on a Systematic Review.

• Main Authors: Hannah Yejin Kim (Author), Anne-Grete Märtson (Author), Erwin Dreesen (Author), Isabel Spriet (Author), Sebastian G. Wicha (Author), Andrew J. McLachlan (Author), Jan-Willem Alffenaar (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Precision dosing for many antifungal drugs is now recommended. Saliva sampling is considered as a non-invasive alternative to plasma sampling for therapeutic drug monitoring (TDM). However, there are currently no clinically validated saliva models available. The aim of this study is firstly, to cond...