p300 exerts an epigenetic role in chronic neuropathic pain through its acetyltransferase activity in rats following chronic constriction injury (CCI)

• Main Authors: Zhu Xiao-Yan (Author), Huang Chang-Sheng (Author), Li Qian (Author), Chang Rui-min (Author), Song Zong-bing (Author), Zou Wang-yuan (Author), Guo Qu-Lian (Author)
• Format: Book
• Published: SAGE Publishing, 2012-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Neuropathic pain is detrimental to human health; however, its pathogenesis still remains largely unknown. Overexpression of pain-associated genes and increased nociceptive somato-sensitivity are well observed in neuropathic pain. The...