The Coincidence Between Increasing Age, Immunosuppression, and the Incidence of Patients With Glioblastoma

• Главные авторы: Erik Ladomersky (Автор), Denise M. Scholtens (Автор), Masha Kocherginsky (Автор), Elizabeth A. Hibler (Автор), Elizabeth T. Bartom (Автор), Sebastian Otto-Meyer (Автор), Lijie Zhai (Автор), Kristen L. Lauing (Автор), Jaehyuk Choi (Автор), Jeffrey A. Sosman (Автор), Jennifer D. Wu (Автор), Bin Zhang (Автор), Rimas V. Lukas (Автор), Derek A. Wainwright (Автор)
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• Опубликовано: Frontiers Media S.A., 2019-03-01T00:00:00Z.
• Предметы: article
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Background: Glioblastoma (GBM) is the most aggressive primary brain tumor in adults and is associated with a median overall survival (mOS) of 16-21 months. Our previous work found a negative association between advanced aging and the survival benefit after treatment with immunotherapy in an experime...