Connexin 37 Regulates the Kv1.3 Pathway and Promotes the Development of Atherosclerosis

• Main Authors: Minqi Liao (Author), Lihua Chen (Author), Jiongbin Lu (Author), Guangzhu Liang (Author), Yongzhao Yao (Author), Shumin Ouyang (Author), Yanhua Yang (Author), Zhengwei Jian (Author), Suxia Guo (Author)
• Format: Book
• Published: Hindawi Limited, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective. To investigate the mechanism of Connexin 37 (Cx37) and Kv1.3 pathways in atherosclerosis (AS). Methods. ApoE-/- mice were given a high-fat diet to establish atherosclerosis (AS) model, and macrophages in mice were isolated and extracted to transfect Cx37 vectors with silencing or overexpr...