Modeling the efficacy of CRISPR gene drive for snail immunity on schistosomiasis control.

• Main Authors: Richard E Grewelle (Author), Javier Perez-Saez (Author), Josh Tycko (Author), Erica K O Namigai (Author), Chloe G Rickards (Author), Giulio A De Leo (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

CRISPR gene drives could revolutionize the control of infectious diseases by accelerating the spread of engineered traits that limit parasite transmission in wild populations. Gene drive technology in mollusks has received little attention despite the role of freshwater snails as hosts of parasitic...