Nonerythropoietic Erythropoietin Mimetic Peptide ARA290 Ameliorates Chronic Stress-Induced Depression-Like Behavior and Inflammation in Mice

• Main Authors: Guanglei Xu (Author), Tao Zou (Author), Lijiao Deng (Author), Guang Yang (Author), Tingting Guo (Author), Yi Wang (Author), Chunxiao Niu (Author), Qianqian Cheng (Author), Xiqin Yang (Author), Jie Dong (Author), Jiyan Zhang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Major depressive disorder (MDD) is a highly prevalent psychiatric disorder. But the treatment of depression remains challenging. Anti-inflammatory treatments frequently produce antidepressant effects. EPO-derived helix-B peptide ARA290 has been reported to retain the anti-inflammatory and tissue-pro...