Vismodegib: A smoothened inhibitor for the treatment of advanced basal cell carcinoma
Incidence of basal cell carcinoma (BCC), the most common skin cancer in humans, is rising. Surgery is the mainstay of treatment but there is no standard of care for locally advanced or metastatic disease. Hedgehog signaling proteins are critical for cell growth and differentiation during embryogenes...
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Wolters Kluwer Medknow Publications,
2013-01-01T00:00:00Z.
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