Keratinocyte Growth Factor 2 Ameliorates UVB-Induced Skin Damage via Activating the AhR/Nrf2 Signaling Pathway

• Main Authors: Shuang Gao (Author), Keke Guo (Author), Yu Chen (Author), Jungang Zhao (Author), Rongrong Jing (Author), Lusheng Wang (Author), Xuenan Li (Author), Zhenlin Hu (Author), Nuo Xu (Author), Xiaokun Li (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Exposure to ultraviolet B (UVB) can cause skin damage through oxidative stress, DNA damage, and apoptosis. Keratinocyte growth factor (KGF) has been shown to reduce the content of intracellular reactive oxygen species (ROS) following UVB exposure, a role that is crucial for the efficient...