Case Report: Respiratory paralysis associated with polymyxin B therapy

• Main Authors: Yachan Ning (Author), Yanqi Chu (Author), You Wu (Author), Ying Huang (Author), Chunmei Wang (Author), Li Jiang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Polymyxin B (PMB) and colistin are bactericidal polypeptide antibiotics discovered in 1947 and 1949 for the treatment of gram-negative bacterial infections. Polymyxin was used clinically in the 1950s, but it was gradually replaced by other antibiotics in the 1980s because of its high nephrotoxicity...