The ovarian estrogen synthesis function was impaired in Y123F mouse and partly restored by exogenous FSH supplement

• Main Authors: Xiaoyu Tu (Author), Miao Liu (Author), Jianan Tang (Author), Yu Zhang (Author), Yan Shi (Author), Lin Yu (Author), Zhaogui Sun (Author)
• Format: Book
• Published: BMC, 2018-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background LepR tyrosine site mutation mice (Y123F) exhibit decreased serum E2 levels, immature reproductive organs, infertility as well as metabolic abnormalities. Although the actions of leptin and lepR in the control of reproductive function are thought to be exerted mainly via the hypot...