The atypical β‐blocker S‐oxprenolol reduces cachexia and improves survival in a rat cancer cachexia model

• Main Authors: Luping Yuan (Author), Jochen Springer (Author), Sandra Palus (Author), Silvia Busquets (Author), Queralt Jové (Author), Edson Alves de Lima Junior (Author), Markus S. Anker (Author), Stephan vonHaehling (Author), Natalia Álvarez Ladrón (Author), Oliver Millman (Author), Annemijn Oosterlee (Author), Agata Szymczyk (Author), Francisco Javier López‐Soriano (Author), Stefan D. Anker (Author), Andrew J.S. Coats (Author), Josep M. Argiles (Author)
• Format: Book
• Published: Wiley, 2023-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Beta‐blockers and selected stereoisomers of beta‐blockers, like bisoprolol and S‐pindolol (ACM‐001), have been shown to be effective in preclinical cancer cachexia models. Here, we tested the efficacy of stereoisomers of oxprenolol in two preclinical models of cancer cachexia-the...