Vaccination with a chikungunya virus-like particle vaccine exacerbates disease in aged mice.

INTRODUCTION:Chikungunya virus (CHIKV) is a re-emerging pathogen responsible for causing outbreaks of febrile disease accompanied with debilitating joint pain. Symptoms typically persist for two weeks, but more severe and chronic chikungunya illnesses have been reported, especially in the elderly. C...

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主要な著者: Maria T Arévalo (著者), Ying Huang (著者), Cheryl A Jones (著者), Ted M Ross (著者)
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出版事項: Public Library of Science (PLoS), 2019-04-01T00:00:00Z.
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