Ergosta-7,9(11),22-trien-3β-ol Attenuates Inflammatory Responses via Inhibiting MAPK/AP-1 Induced IL-6/JAK/STAT Pathways and Activating Nrf2/HO-1 Signaling in LPS-Stimulated Macrophage-like Cells

• Main Authors: Yi-Ping Huang (Author), Dar-Ren Chen (Author), Wen-Jen Lin (Author), Yu-Hsien Lin (Author), Jiann-Yeu Chen (Author), Yueh-Hsiung Kuo (Author), Jing-Gung Chung (Author), Te-Chun Hsia (Author), Wen-Tsong Hsieh (Author)
• Format: Book
• Published: MDPI AG, 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Chronic inflammation induces autoimmune disorders and chronic diseases. Several natural products activate nuclear factor erythroid 2-related factor 2 (Nrf2) signaling, attenuating inflammatory responses. Ergosta-7,9(11),22-trien-3β-ol (EK100) isolated from <i>Cordyceps militaris</i> show...