Plasma concentration and eGFR in preterm and term neonates receiving gentamicin or successive amikacin therapy

• Main Authors: Bonifasius Siyuka Singu (Author), Milka Ndapandula Ndeunyema (Author), Ene I. Ette (Author), Clarissa Hildegard Pieper (Author), Roger Karel Verbeeck (Author)
• Format: Book
• Published: BMC, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Gentamicin and amikacin are aminoglycoside antibiotics which are renally excreted and known to be nephrotoxic. Estimate of glomerular filtration rate (eGFR) per body surface area is lower in neonates than in adults and exposure to these drugs could lead to more suppression in kid...