Selective Small Molecule Myeloid Cell Leukemia-1 (MCL-1) Inhibitors: Novel Agents in Cancer Therapy

• Główni autorzy: Hoda Sobhy Ibrahim (Autor), Deena S. Lasheen (Autor), Rabah A. T. Serya (Autor), Dalal Abd-ELRahm (Autor)
• Format: Książka
• Wydane: Ain Shams University, 2019-12-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Apoptosis is a normal physiological process which is very crucial to maintain tissue homeostasis. Dysregulated apoptosis can lead to various diseases as cancer. Thus, evasion of apoptosis stands out as a key hallmark of cancer cells. Bcl-2 family of proteins is the key modulator of the mitochondrial...