The Parkinson's disease-associated protein DJ-1 plays a positive nonmitochondrial role in endocytosis in Dictyostelium cells

• Main Authors: Suwei Chen (Author), Sarah J. Annesley (Author), Rasha A. F. Jasim (Author), Vanessa J. Musco (Author), Oana Sanislav (Author), Paul R. Fisher (Author)
• Format: Book
• Published: The Company of Biologists, 2017-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The loss of function of DJ-1 caused by mutations in DJ1 causes a form of familial Parkinson's disease (PD). However, the role of DJ-1 in healthy and in PD cells is poorly understood. Even its subcellular localization in mammalian cells is uncertain, with both cytosolic and mitochondrial locatio...