The Parkinson's disease-associated protein DJ-1 plays a positive nonmitochondrial role in endocytosis in Dictyostelium cells

• Autores principales: Suwei Chen (Autor), Sarah J. Annesley (Autor), Rasha A. F. Jasim (Autor), Vanessa J. Musco (Autor), Oana Sanislav (Autor), Paul R. Fisher (Autor)
• Formato: Libro
• Publicado: The Company of Biologists, 2017-10-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

The loss of function of DJ-1 caused by mutations in DJ1 causes a form of familial Parkinson's disease (PD). However, the role of DJ-1 in healthy and in PD cells is poorly understood. Even its subcellular localization in mammalian cells is uncertain, with both cytosolic and mitochondrial locatio...