Supplement Treatment with NAC and Omega-3 Polyunsaturated Fatty Acids during Pregnancy Partially Prevents Schizophrenia-Related Outcomes in the Poly I:C Rat Model

• Main Authors: Henriette Edemann-Callesen (Author), Nadine Bernhardt (Author), Elizabeth Barroeta Hlusicka (Author), Franziska Hintz (Author), Bettina Habelt (Author), Rebecca Winter (Author), Isabell Neubert (Author), Meike Pelz (Author), Alexandra Filla (Author), Maria Luisa Soto-Montenegro (Author), Christine Winter (Author), Ravit Hadar (Author)
• Format: Book
• Published: MDPI AG, 2023-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Heightened levels of inflammation and oxidative stress are thought to be involved in the pathophysiology of schizophrenia. We aimed to assess whether intake of anti-inflammatory and anti-oxidant drugs during pregnancy prevents later schizophrenia-related outcomes in a neurodevelopmental...