Ahsa1 and Hsp90 activity confers more severe craniofacial phenotypes in a zebrafish model of hypoparathyroidism, sensorineural deafness and renal dysplasia (HDR)

• Váldodahkkit: Kelly Sheehan-Rooney (Dahkki), Mary E. Swartz (Dahkki), Feng Zhao (Dahkki), Dong Liu (Dahkki), Johann K. Eberhart (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: The Company of Biologists, 2013-09-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

SUMMARY The severity of most human birth defects is highly variable. Our ability to diagnose, treat and prevent defects relies on our understanding of this variability. Mutation of the transcription factor GATA3 in humans causes the highly variable hypoparathyroidism, sensorineural deafness and rena...