Mortality in human sepsis is associated with downregulation of Toll-like receptor 2 and CD14 expression on blood monocytes

Mortality in human sepsis is associated with downregulation of Toll-like receptor 2 and CD14 expression on blood monocytes

<p>Abstract</p> <p>Pattern recognition receptors are a key component of the first line host defense against infection, recognizing specific microbial products. We hypothesize that monocyte hyporesponsiveness in human sepsis is associated with a downregulation of the pattern recogni...

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Main Authors: Dodt Christoph (Author), Sayk Friedhelm (Author), van Bremen Tobias (Author), Goldmann Torsten (Author), Luitjens Karen (Author), Schaaf Bernhard (Author), Dalhoff Klaus (Author), Droemann Daniel (Author)
Format: Book
Published: BMC, 2009-04-01T00:00:00Z.
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