An ex vivo model for studying hepatic schistosomiasis and the effect of released protein from dying eggs.

An ex vivo model for studying hepatic schistosomiasis and the effect of released protein from dying eggs.

BACKGROUND:We report the use of an ex vivo precision cut liver slice (PCLS) mouse model for studying hepatic schistosomiasis. In this system, liver tissue is unfixed, unfrozen, and alive for maintenance in culture and subsequent molecular analysis. METHODS AND FINDINGS:Using thick naive mouse liver...

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Main Authors: Geoffrey N Gobert (Author), Sujeevi K Nawaratna (Author), Marina Harvie (Author), Grant A Ramm (Author), Donald P McManus (Author)
Format: Book
Published: Public Library of Science (PLoS), 2015-05-01T00:00:00Z.
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