SHP2 Inhibitors Show Anti-Myeloma Activity and Synergize With Bortezomib in the Treatment of Multiple Myeloma

Multiple myeloma (MM) is a plasma cell malignancy that remains incurable. The protein tyrosine phosphatase SHP2 is a central node regulating RAS/mitogen-activated protein kinase (MAPK)/extracellular signal regulated kinase (ERK) signaling pathway which plays a crucial role in the pathogenesis and pr...

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Main Authors: Pan Zhou (Author), Mengyu Xiao (Author), Weiya Li (Author), Xiaobai Sun (Author), Yanliang Bai (Author), Feiying Meng (Author), Zunmin Zhu (Author), Weiping Yuan (Author), Kai Sun (Author)
Format: Book
Published: Frontiers Media S.A., 2022-04-01T00:00:00Z.
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