Decreased circulating IPA levels identify subjects with metabolic comorbidities: A multi-omics study

• Main Authors: Marta Ballanti (Author), Lorenzo Antonetti (Author), Maria Mavilio (Author), Viviana Casagrande (Author), Alessandro Moscatelli (Author), Daniele Pietrucci (Author), Adelaide Teofani (Author), Chiara Internò (Author), Marina Cardellini (Author), Omero Paoluzi (Author), Giovanni Monteleone (Author), Philippe Lefebvre (Author), Bart Staels (Author), Geltrude Mingrone (Author), Rossella Menghini (Author), Massimo Federici (Author)
• Format: Book
• Published: Elsevier, 2024-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In recent years several experimental observations demonstrated that the gut microbiome plays a role in regulating positively or negatively metabolic homeostasis. Indole-3-propionic acid (IPA), a Tryptophan catabolic product mainly produced by C. Sporogenes, has been recently shown to exert either fa...