In Vivo TLR9 Inhibition Attenuates CpG-Induced Myocardial Dysfunction

The involvement of toll-like receptor 9 (TLR9), a receptor for bacterial DNA, in septic cardiac depression has not been clarified in vivo. Thus, the aim of the study was to test possible TLR9 inhibitors (H154-thioate, IRS954-thioate, and chloroquine) for their ability to protect the cardiovascular s...

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Main Authors: O. Boehm (Author), P. Markowski (Author), M. van der Giet (Author), V. Gielen (Author), A. Kokalova (Author), C. Brill (Author), A. Hoeft (Author), G. Baumgarten (Author), R. Meyer (Author), P. Knuefermann (Author)
Formato: Livro
Publicado em: Hindawi Limited, 2013-01-01T00:00:00Z.
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