Exploring the potential mechanism of Radix Bupleuri in the treatment of sepsis: a study based on network pharmacology and molecular docking

• Główni autorzy: Hao Wang (Autor), Wei Xiong (Autor), Yongchu Laram (Autor), Li Hu (Autor), Wu Zhong (Autor), Yingchun Hu (Autor)
• Format: Książka
• Wydane: BMC, 2024-10-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Abstract Aim To explore, using network pharmacology and RNA-seq technologies, potential active targets and mechanisms underpinning Radix Bupleuri's effectiveness during sepsis treatment. Methods Following the Sepsis-3.0 criteria, the research cohort, comprising 23 sepsis patients and 10 healthy...