Pharmacogenetic Variation in Over 100 Genes in Patients Receiving Acenocumarol

• Main Authors: Vanessa Gonzalez-Covarrubias (Author), Javier Urena-Carrion (Author), Beatriz Villegas-Torres (Author), J. Eduardo Cossío-Aranda (Author), Sergio Trevethan-Cravioto (Author), Raul Izaguirre-Avila (Author), O. Javier Fiscal-López (Author), Xavier Soberon (Author)
• Format: Book
• Published: Frontiers Media S.A., 2017-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Coumarins are widely prescribed worldwide, and in Mexico acenocumarol is the preferred form. It is well known that despite its efficacy, coumarins show a high variability for dose requirements. We investigated the pharmacogenetic variation of 110 genes in patients receiving acenocumarol using a targ...