Design and characterisation of piperazine-benzofuran integrated dinitrobenzenesulfonamide as Mycobacterium tuberculosis H37Rv strain inhibitors

• Main Authors: Vallabhaneni S. Murthy (Author), Yasinalli Tamboli (Author), Vagolu Siva Krishna (Author), Dharmarajan Sriram (Author), Siddique Akber Ansari (Author), Abdullah A. Alarfaj (Author), Abdurahman H. Hirad (Author), Vijayaparthasarathi Vijayakumar (Author)
• Format: Book
• Published: Taylor & Francis Group, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Molecular hybridisation of four bioactive fragments piperazine, substituted-benzofuran, amino acids, and 2,4-dinitrobenzenesulfonamide as single molecular architecture was designed. A series of new hybrids were synthesised and subjected to evaluation for their inhibitory activity against Mycobacteri...