Collaborative Study of Thresholds for Mutagens: Adaptive Responses in the Micronucleus Test and Gene Induction by Mutagenic Treatments

• Main Authors: Shizuyo Sutou (Author), Akiko Koeda (Author), Kana Komatsu (Author), Toshiyuki Shiragiku (Author), Hiroshi Seki (Author), Toshiyuki Kudo (Author)
• Format: Book
• Published: SAGE Publishing, 2024-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background We have been conducting a collaborative study on the thresholds of mutagens. In our previous examinations of cell activity and cell proliferation as endpoints, both displayed hormesis. This time, we conducted experiments to determine thresholds using the micronucleus test as an endpoint....