γ-Aminobutyric AcidB(GABAB)-Receptor Mediation of Different In Vivo Effects of γ-Butyrolactone

• Main Authors: Mauro A.M. Carai (Author), Carla Lobina (Author), Paola Maccioni (Author), Claudia Cabras (Author), Giancarlo Colombo (Author), Gian Luigi Gessa (Author)
• Format: Book
• Published: Elsevier, 2008-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The endogenous brain constituent, γ-hydroxybutyric acid (GHB), as well as its prodrug, γ-butyrolactone (GBL), have recently gained interest in the drug addiction field due to their abuse potential and fatalities caused by overdose. It is known that GHB has two sites of actions: the γ-aminobutyric ac...