Novel Gemcitabine-Re(I) Bisquinolinyl Complex Combinations and Formulations With Liquid Crystalline Nanoparticles for Pancreatic Cancer Photodynamic Therapy

• Main Authors: Hui Shan Liew (Author), Chun-Wai Mai (Author), Mohd Zulkefeli (Author), Thiagarajan Madheswaran (Author), Lik Voon Kiew (Author), Lesley Jia Wei Pua (Author), Ling Wei Hii (Author), Wei Meng Lim (Author), May Lee Low (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

With less than 10% of 5-year survival rate, pancreatic ductal adenocarcinoma (PDAC) is known to be one of the most lethal types of cancer. Current literature supports that gemcitabine is the first-line treatment of PDAC. However, poor cellular penetration of gemcitabine along with the acquired and i...