Diosmin Alleviates Doxorubicin-Induced Liver Injury via Modulation of Oxidative Stress-Mediated Hepatic Inflammation and Apoptosis via NfkB and MAPK Pathway: A Preclinical Study

• Главные авторы: Abdullah F. AlAsmari (Автор), Metab Alharbi (Автор), Faleh Alqahtani (Автор), Fawaz Alasmari (Автор), Mohammed AlSwayyed (Автор), Sami I. Alzarea (Автор), Ibrahim A. Al-Alallah (Автор), Adel Alghamdi (Автор), Hassan M. Hakami (Автор), Meshal K. Alyousef (Автор), Youssef Sari (Автор), Nemat Ali (Автор)
• Формат: ‌
• Опубликовано: MDPI AG, 2021-12-01T00:00:00Z.
• Предметы: article
• Online-ссылка: Connect to this object online.

Hepatotoxicity caused by chemotherapeutic drugs (e.g., doxorubicin) is of critical concern in cancer therapy. This study focused on investigating the modulatory effects of diosmin against doxorubicin-induced hepatotoxicity in Male Wistar rats. Male Wistar rats were randomly divided into four groups:...