Diosmin Alleviates Doxorubicin-Induced Liver Injury via Modulation of Oxidative Stress-Mediated Hepatic Inflammation and Apoptosis via NfkB and MAPK Pathway: A Preclinical Study

• Main Authors: Abdullah F. AlAsmari (Author), Metab Alharbi (Author), Faleh Alqahtani (Author), Fawaz Alasmari (Author), Mohammed AlSwayyed (Author), Sami I. Alzarea (Author), Ibrahim A. Al-Alallah (Author), Adel Alghamdi (Author), Hassan M. Hakami (Author), Meshal K. Alyousef (Author), Youssef Sari (Author), Nemat Ali (Author)
• Format: Book
• Published: MDPI AG, 2021-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Hepatotoxicity caused by chemotherapeutic drugs (e.g., doxorubicin) is of critical concern in cancer therapy. This study focused on investigating the modulatory effects of diosmin against doxorubicin-induced hepatotoxicity in Male Wistar rats. Male Wistar rats were randomly divided into four groups:...