Designing a Topical Nanoliposomal Formulation of Ruxolitinib Phosphate

• Main Authors: Atefeh Naeimifar (Author), Saman Ahmad Nasrollahi (Author), Hamid Akbari Javar (Author), Mansoor Nassiri Kashani (Author), Alireza Firooz (Author), Mohamadreza Rouini (Author)
• Format: Book
• Published: Tabriz University of Medical Sciences, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: The JAK-STAT pathway has been revealed to play a crucial role in the dysregulation of immune responses in autoimmune skin disorders. Ruxolitinib, a selective inhibitor of JAK1 and JAK2, potently suppresses cytokine signaling. Methods: A topical emulgel containing ruxolitinib nanoliposome...