Anti-cancer Drug Response Prediction Using Neighbor-Based Collaborative Filtering with Global Effect Removal

• Autori principali: Hui Liu (Autore), Yan Zhao (Autore), Lin Zhang (Autore), Xing Chen (Autore)
• Natura: Libro
• Pubblicazione: Elsevier, 2018-12-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Patients of the same cancer may differ in their responses to a specific medical therapy. Identification of predictive molecular features for drug sensitivity holds the key in the era of precision medicine. Human cell lines have harbored most of the same genetic changes found in patients' tumors...